Saturday, November 18, 2023

Reckless prescription of QUETIAPINE FUMARATE for elderly neighbor with dementia ?

My 90 year old neighbor Rita on the same floor has been diagnosed with dementia. While checking her mail today I was shown a bottle of prescription medicine. I thought it was for PAIN as Rita has arthritis and frequently complains about pain in her hip. Curious , I wrote the name of the prescription: " QUETIAPINE FUMARATE . I was disturbed by this warning when checking the purpose of the drug : [Quetiapine-related toxicity is typically associated with central nervous system (CNS) depression, leading to slurred speech, sedation, and hypotension. Notably, quetiapine has a black box warning associated with death in older adults with dementia, and higher doses are believed to exacerbate this risk (1).Dec 2, 2022[ I lack the medical knowledge to question this. But there is cause for concern here. I think Rita would be safer now in HOSPICE care and just made COMFORTABLE and free of pain. This particular drug I read is a generic form of Seroquel which was wrongly prescribed to my 89 year old mother in the last months of her life. The family got her off it as it caused nightmares and was BLACK BOXED for the elderly. To be sure 90 year old Rita should not be living alone as she is an accident waiting to happen. Today there was nothing but junk mail for both Rita and I. [ Another consideration : should a 90 year old woman with dementia-LIVING ALONE - be unsupervised with a dangerous prescription ? Rita will FORGET what she was just told !] [OVERVIEW: Seroquel, which is known generically as quetiapine fumarate, is an atypical antipsychotic medication which was approved by the FDA in 1997. It is approved for treatment of schizophrenia, but it is also commonly used off-label for treatment of anxiety, obsessive dementia, compulsive disorders and autism. AstraZeneca has been accused of heavily marketing Seroquel for “off-label” uses which the FDA has not approved or determined to be safe and effective. Some experts have estimated that as much as 70% of all Seroquel prescriptions were for unapproved uses. Seroquel has been used by more than 19 million people worldwide. It is one of the most profitable drugs for AstraZeneca, with annual sales of about $2.8 billion]

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Ron